STXBP1 anticorps (AA 11-110) (FITC)
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- Antigène Voir toutes STXBP1 Anticorps
- STXBP1 (Syntaxin Binding Protein 1 (STXBP1))
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Épitope
- AA 11-110
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Reactivité
- Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp STXBP1 est conjugé à/à la FITC
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Réactivité croisée
- Rat
- Homologie
- Human,Mouse,Dog,Pig,Horse,Chicken
- Purification
- Purified by Protein A.
- Immunogène
- KLH conjugated synthetic peptide derived from human Munc18
- Isotype
- IgG
- Top Product
- Discover our top product STXBP1 Anticorps primaire
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- Indications d'application
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Agent conservateur
- ProClin
- Précaution d'utilisation
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Stock
- -20 °C
- Stockage commentaire
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Date de péremption
- 12 months
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- Antigène
- STXBP1 (Syntaxin Binding Protein 1 (STXBP1))
- Autre désignation
- STXBP1/Munc18 (STXBP1 Produits)
- Synonymes
- anticorps MUNC18-1, anticorps NSEC1, anticorps P67, anticorps RBSEC1, anticorps UNC18, anticorps AI317162, anticorps AI326233, anticorps MMS10-G, anticorps Ms10g, anticorps Munc-18a, anticorps Munc18-1, anticorps N-sec1, anticorps Rb-sec1, anticorps Sxtbp1, anticorps Unc18-1, anticorps Unc18h, anticorps nsec1, anticorps fj43h10, anticorps stxbp1, anticorps wu:fj36d12, anticorps wu:fj43h10, anticorps zgc:114171, anticorps rop, anticorps unc18, anticorps hunc18, anticorps rbsec1, anticorps munc18-1, anticorps MGC146482, anticorps ANC18HA, anticorps NSEC1A, anticorps Sec1, anticorps n-sec1, anticorps nSec1, anticorps rbSec1, anticorps rbSec1A, anticorps rbSec1B, anticorps UNC18A, anticorps si:rp71-10d23.3, anticorps syntaxin binding protein 1, anticorps syntaxin binding protein 1a, anticorps syntaxin binding protein 1 L homeolog, anticorps syntaxin binding protein 1b, anticorps STXBP1, anticorps Stxbp1, anticorps stxbp1a, anticorps stxbp1, anticorps Tb09.160.0780, anticorps stxbp1.L, anticorps stxbp1b
- Sujet
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Synonyms: Munc 18 1, Munc 18a, NSec1, p67, Rb sec1, STXBP1, Syntaxin binding protein 1, Unc 18 homolog, Unc 18A, Unc18 1, STXB1_HUMAN, Syntaxin-binding protein 1, MUNC18-1, N-Sec1, Protein unc-18 homolog 1, Unc18-1, Protein unc-18 homolog A, Unc-18A, p67.
Background: Munc18 may participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP binding proteins. It is essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Munc18 can interact with syntaxins 1, 2, and 3 but not syntaxin 4. It may play a role in determining the specificity of intracellular fusion reactions.Mutations in Munc18 can result in accumulations of acetylcholine and paralytic phenotype suggestive of a neurotransmitter release defect. Two Munc18 isoforms have recently been identified. Munc18-1 has been shown to be primarily expressed in brain, while Munc18-2 is expressed in most tissues.
- ID gène
- 6812
- UniProt
- P61764
- Pathways
- Synaptic Vesicle Exocytosis, Dicarboxylic Acid Transport
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