NOX5 anticorps (C-Term) (FITC)

N° du produit ABIN8013794

Cet anticorps Lapin Polyclonal détecte spécifiquement NOX5 dans FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour NOX5 anticorps (C-Term) (FITC) (ABIN8013794)

Antigène: NOX5 (NADPH Oxidase 5 (NOX5))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NOX5 est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Détail du produit anti-NOX5 anticorps (FITC)

Épitope: C-Term

Fonction: Anti-NADPH oxidase 5 NOX5 Antibody FITC Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human NOX5.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur NOX5

Antigène: NOX5 (NADPH Oxidase 5 (NOX5))

Autre désignation: NOX5

Sujet:

Background: NOX5 (Nadph Oxidase 5), also known as NOX5A or NOX5B, is a protein which in humans is encoded by the NOX5 gene. The International Radiation Hybrid Mapping Consortium mapped the NOX5 gene to chromosome 15. NOX5 is a novel NADPH oxidase that generates superoxide and functions as an H+ channel in a Ca2+-dependent manner. Banfi et al. (2001) found that, when heterologously expressed, NOX5 was quiescent in unstimulated cells. However, in response to elevations of the cytosolic Ca2+ concentration, it generated large amounts of superoxide. Using RT-PCR and Southern and Western blot analyses, Kamiguti et al. (2005) identified NOX5 as a flavin-containing Ca2+-dependent oxidase present in hairy leukemic cells (HC), but not normal B cells.

Gene Full Name: NADPH oxidase 5

Sequence Similarities: Contains 4 EF-hand domains.

UniProt: Q96PH1

Pathways: Proton Transport