2B4 anticorps (AA 20-372)

N° du produit ABIN8013997

Cet anticorps anti-2B4 Polyclonal Lapin (ABIN8013997) détecte spécifiquement 2B4 dans WB et ELISA. L’anticorps est réactif avec des échantillons de Rat.

Aperçu rapide pour 2B4 anticorps (AA 20-372) (ABIN8013997)

Antigène: 2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp 2B4 est non-conjugé

Application: Western Blotting (WB), ELISA

Classe de qualité: Carrier-free

Détail du produit anti-2B4 anticorps

Épitope: AA 20-372

Fonction: Anti-2B4/Cd244 Antibody

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-2B4/Cd244 Antibody. Tested in ELISA, WB applications. This antibody reacts with Rat.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived rat 2B4/Cd244 recombinant protein (Position: Q20-Q372).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Rat ELISA, 0.1-0.5 μg/mL,

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur 2B4

Antigène: 2B4 (CD244) (Natural Killer Cell Receptor 2B4 (CD244))

Autre désignation: Cd244

Sujet:

Background: CD244 (Cluster of Differentiation 244) is a human protein encoded by the CD244 gene. It is also known as Natural Killer Cell Receptor 2B4. Tangye et al. (1999) mapped the 2B4 gene to 1q22. Suzuki et al. (2008) identified a functional single-nucleotide polymorphism (SNP) in the CD244 gene that contributes to rheumatoid arthritis susceptibility. Functional analysis by Boles et al. (1999) demonstrated that engagement of 2B4 with specific antibody activates NK cytolytic activity. Using recombinant human NK cell-activating ligand 2B4 fused to domains 3 and 4 of rodent Cd4 and flow cytometric analysis, Brown et al. (1998) demonstrated that CD48 binds to 2B4. Watzl et al. (2000) showed that antibody-mediated cross-linking of 2B4 leads to its rapid tyrosine phosphorylation, which is necessary for 2B4-mediated killer cell activity.

Gene Full Name: CD244 Molecule

Poids moléculaire: 50 kDa

ID gène: 64025

UniProt: E9PT21