Netrin 3 anticorps (AA 51-473) (PE)

N° du produit ABIN8014391

Cet anticorps Lapin Polyclonal détecte spécifiquement Netrin 3 dans FACS. Il présente une réactivité avec des échantillons de Humain et Rat.

Aperçu rapide pour Netrin 3 anticorps (AA 51-473) (PE) (ABIN8014391)

Antigène: Netrin 3 (Ntn3)

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Netrin 3 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Détail du produit anti-Netrin 3 anticorps (PE)

Épitope: AA 51-473

Fonction: Anti-NTN3 Antibody PE Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human NTN3 recombinant protein (Position: R51-R473).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur Netrin 3

Antigène: Netrin 3 (Ntn3)

Autre désignation: NTN3

Sujet:

Background: Netrins are a family of highly conserved proteins responsible for axon guidance and cell movement throughout neural development. Netrins can be divided into secreted netrins (netrin 1,3,4 and 5) and membrane-tethered glycophosphatidylinositol (GPI)-linked netrins (netrin G1 and G2).Secreted netrins carry their function via interaction with several receptors that include the deleted in colorectal (DCC) family, and the uncoordinated-5 (UNC5-A through UNC5-D) family.Netrin-3 was discovered in 1997 using sequence homology searching of netrin-2. Similarly to other netrins, Netrin-3 plays an important role in the development of the nervous system. Netrin-3 structure consist of a laminin-like domain located on the N-terminal, three epidermal growth factors like repeats (EGF), and a C-terminal netrin-like domain (NTR). Mutations in NTN3, the gene encoding netrin-3 was found to be associated with the development of several carcinomas.

Gene Full Name: netrin 3

ID gène: 4917

UniProt: O00634

Pathways: Regulation of Muscle Cell Differentiation