NPS anticorps (C-Term) (Fluoro594)

N° du produit ABIN8014992

L’anticorps anti-NPS Polyclonal Lapin est utilisé pour la détection de NPS dans des échantillons de Souris et Rat. Il a été validé pour FACS.

Aperçu rapide pour NPS anticorps (C-Term) (Fluoro594) (ABIN8014992)

Antigène: NPS (Neuropeptide S (NPS))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NPS est conjugé à/à la Fluoro594

Application: Flow Cytometry (FACS)

Détail du produit anti-NPS anticorps (Fluoro594)

Épitope: C-Term

Fonction: Anti-Neuropeptide S/NPS Antibody Fluoro594 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human Neuropeptide S, which shares 80% amino acid (aa) sequence identity with both mouse and rat Neuropeptide S.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur NPS

Antigène: NPS (Neuropeptide S (NPS))

Autre désignation: NPS

Sujet:

Background: Neuropeptide S (NPS) is a neuropeptide found in human and mammalian brain, mainly produced by neurons in the amygdala and between Barrington's nucleus and the locus coeruleus, although NPS-responsive neurons extend projections into many other brain areas. NPS binds specifically to a G protein-coupled receptor, NPSR. Animal studies show that NPS suppresses anxiety and appetite, induces wakefulness and hyperactivity, including hyper-sexuality, and plays a significant role in the extinction of conditioned fear.It has also been shown to significantly enhance dopamine activity in the mesolimbic pathway, and inhibits motility and increases permeability in neurocrine fashion acting through NO in the myenteric plexus in rats and humans.

Gene Full Name: neuropeptide S

ID gène: 594857

UniProt: P0C0P6