NFS1 anticorps (AA 107-356) (HRP)

N° du produit ABIN8015324

Cet anticorps Lapin Polyclonal détecte spécifiquement NFS1 dans WB, IHC et ELISA. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour NFS1 anticorps (AA 107-356) (HRP) (ABIN8015324)

Antigène: NFS1 (NFS1, Cysteine Desulfurase (NFS1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NFS1 est conjugé à/à la HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-NFS1 anticorps (HRP)

Épitope: AA 107-356

Fonction: Anti-NFS1 Antibody HRP Conjugated

Homologie: Human NFS1 shares 96.4%,96% amino acid (aa) sequence identity with mouse,rat NFS1,respectively.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human NFS1 recombinant protein (Position: R107-L356). Human NFS1 shares 96.4% and 96% amino acid (aa) sequence identity with mouse and rat NFS1, respectively.

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur NFS1

Antigène: NFS1 (NFS1, Cysteine Desulfurase (NFS1))

Autre désignation: NFS1

Sujet:

Background: Cysteine desulfurase, mitochondrial is an enzyme that in humans is encoded by the NFS1 gene. Iron-sulfur clusters are required for the function of many cellular enzymes. The proteins encoded by this gene supply inorganic sulfur to these clusters by removing the sulfur from cysteine, creating alanine in the process. This gene uses alternate in-frame translation initiation sites to generate mitochondrial forms and cytoplasmic/nuclear forms. Selection of the alternative initiation sites is determined by the cytosolic pH . The encoded proteins belong to the class-V family of pyridoxal phosphate-dependent aminotransferases. Alternatively spliced transcript variants have been described.

Gene Full Name: NFS1 cysteine desulfurase

ID gène: 9054

UniProt: Q9Y697

Pathways: Transition Metal Ion Homeostasis