NPLOC4 anticorps (AA 1-495) (HRP)

N° du produit ABIN8016711

L’anticorps anti-NPLOC4 Polyclonal Lapin est utilisé pour la détection de NPLOC4 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, ELISA et IHC.

Aperçu rapide pour NPLOC4 anticorps (AA 1-495) (HRP) (ABIN8016711)

Antigène: NPLOC4 (Nuclear Protein Localization 4 Homolog (NPLOC4))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NPLOC4 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-NPLOC4 anticorps (HRP)

Épitope: AA 1-495

Fonction: Anti-NPL4/NPLOC4 Antibody HRP Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human NPL4/NPLOC4 recombinant protein (Position: M1-N495).

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur NPLOC4

Antigène: NPLOC4 (Nuclear Protein Localization 4 Homolog (NPLOC4))

Autre désignation: NPLOC4

Sujet:

Background: Nuclear protein localization protein 4 homolog is a protein that in humans is encoded by the NPLOC4 gene. Nuclear protein localization protein 4 (NPL4, NPLOC4) was originally identified as a yeast nuclear transport protein that was later recognized as a critical component of the endoplasmic reticulum-associated degradation (ERAD) pathway. Mammalian NPL4 protein has an amino-terminal ubiquitin-like domain containing a p97 binding site, and a conserved carboxy-terminal zinc finger (NZF) motif responsible for binding ubiquitinated target proteins. NPL4 binds ubiquitin fusion degradation protein 1 (UFD1) to form a heterodimer that associates with the p97 AAA-ATPase, creating a protein complex that mediates delivery of ubiquitinated ER proteins to the proteasome.

Gene Full Name: NPL4 homolog, ubiquitin recognition factor

ID gène: 55666

UniProt: Q8TAT6