Occludin anticorps (AA 358-520) (HRP)

N° du produit ABIN8017900

Cet anticorps anti-Occludin Polyclonal Lapin conjugué à HRP (ABIN8017900) détecte spécifiquement Occludin dans WB, IHC et ELISA. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour Occludin anticorps (AA 358-520) (HRP) (ABIN8017900)

Antigène: Occludin (OCLN)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Occludin est conjugé à/à la HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-Occludin anticorps (HRP)

Épitope: AA 358-520

Fonction: Anti-Occludin/OCLN Antibody HRP Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human Occludin,OCLN shares 88.8%,88.2% amino acid (aa) sequence identity with mouse,rat Occludin,OCLN,respectively.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Occludin/OCLN recombinant protein (Position: S358-Q520). Human Occludin/OCLN shares 88.8% and 88.2% amino acid (aa) sequence identity with mouse and rat Occludin/OCLN, respectively.

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur Occludin

Antigène: Occludin (OCLN)

Autre désignation: OCLN

Sujet:

Background: Occludin is an integral membrane protein that is located at tight junctions. It is a member of a family of proteins containing the highly conserved Marvel domain, which contains 4 transmembrane-helix regions. This gene is mapped to 5q13.2. Occludin regulates TGF-beta receptor type I localization for efficient TGF-beta-dependent dissolution of tight junctions during epithelial-mesenchymal transitions. Human Occludin is an essential hepatitis C virus (HCV) cell entry factor that is able to render murine cells infectable with HCV glycoproteins. It has been found that occludin is involved in cell migration and functions to recruit active PI3 kinase to the leading edge, resulting in RAC1 activation and formation of lamellipodia.

Gene Full Name: occludin

ID gène: 100506658

UniProt: Q16625

Pathways: Cell-Cell Junction Organization, Hepatitis C