OPA1 anticorps (AA 296-562) (FITC)

N° du produit ABIN8018229

L’anticorps anti-OPA1 Polyclonal Lapin est utilisé pour la détection de OPA1 dans des échantillons de Humain, Rat et Souris. Il a été validé pour FACS.

Aperçu rapide pour OPA1 anticorps (AA 296-562) (FITC) (ABIN8018229)

Antigène: OPA1 (Optic Atrophy 1 (Autosomal Dominant) (OPA1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp OPA1 est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Détail du produit anti-OPA1 anticorps (FITC)

Épitope: AA 296-562

Fonction: Anti-OPA1 Antibody FITC Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human OPA1 recombinant protein (Position: D296-Q562).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur OPA1

Antigène: OPA1 (Optic Atrophy 1 (Autosomal Dominant) (OPA1))

Autre désignation: OPA1

Sujet:

Background: Dynamin-like 120 kDa protein, mitochondrial is a protein that in humans is encoded by the OPA1 gene. It is mapped to 3q29. This protein regulates mitochondrial fusion and cristae structure in the inner mitochondrial membrane (IMM) and contributes to ATP synthesis and apoptosis. This gene product is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. It is a component of the mitochondrial network. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: OPA1 mitochondrial dynamin like GTPase

ID gène: 4976

UniProt: O60313

Pathways: Tube Formation