Osteocalcin anticorps (AA 52-100) (HRP)

N° du produit ABIN8018497

Cet anticorps anti-Osteocalcin Polyclonal Lapin conjugué à HRP (ABIN8018497) détecte spécifiquement Osteocalcin dans IHC, WB et ELISA. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Osteocalcin anticorps (AA 52-100) (HRP) (ABIN8018497)

Antigène: Osteocalcin (BGLAP)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Osteocalcin est conjugé à/à la HRP

Application: Immunohistochemistry (IHC), Western Blotting (WB), ELISA

Détail du produit anti-Osteocalcin anticorps (HRP)

Épitope: AA 52-100

Fonction: Anti-Osteocalcin/BGLAP Antibody HRP Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: coli-derived human Osteocalcin recombinant protein (Position: Y52-V100). Human Osteocalcin shares 69%,80.9% amino acid (aa) sequence identity with mouse,rat Osteocalcin,respectively.

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived human Osteocalcin recombinant protein (Position: Y52-V100). Human Osteocalcin shares 69% and 80.9% amino acid (aa) sequence identity with mouse and rat Osteocalcin, respectively.

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur Osteocalcin

Antigène: Osteocalcin (BGLAP)

Autre désignation: BGLAP

Sujet:

Background: Osteocalcin, also known as bone gamma-carboxyglutamic acid-containing protein (BGLAP), is a noncollagenous protein found in bone and dentin. In humans, the osteocalcin is encoded by the BGLAP gene. Its receptor is GPRC6A. It is mapped to 1q22. Osteocalcin may play a role in the body's metabolic regulation and is pro-osteoblastic, or bone-building. It acts as a hormone in the body, causing beta cellsin the pancreas to release more insulin, and at the same time ing fat cells to release the hormone adiponectin, which increases sensitivity to insulin. Also, it may play a role in male fertility. And it is found that picomolar amounts of osteocalcin affected insulin secretion and beta-cell proliferation.

Gene Full Name: bone gamma-carboxyglutamate protein

ID gène: 632

UniProt: P02818