Osteocalcin anticorps (AA 52-100)

N° du produit ABIN8018501

Cet anticorps Lapin Polyclonal détecte spécifiquement Osteocalcin dans IHC. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Osteocalcin anticorps (AA 52-100) (ABIN8018501)

Antigène: Osteocalcin (BGLAP)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Osteocalcin est non-conjugé

Application: Immunohistochemistry (IHC)

Classe de qualité: Carrier-free

Détail du produit anti-Osteocalcin anticorps

Épitope: AA 52-100

Fonction: Anti-Osteocalcin/BGLAP Antibody

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: coli-derived human Osteocalcin recombinant protein (Position: Y52-V100). Human Osteocalcin shares 69%,80.9% amino acid (aa) sequence identity with mouse,rat Osteocalcin,respectively.

Attributs du produit: Anti-Osteocalcin/BGLAP Antibody. Tested in IHC applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived human Osteocalcin recombinant protein (Position: Y52-V100). Human Osteocalcin shares 69% and 80.9% amino acid (aa) sequence identity with mouse and rat Osteocalcin, respectively.

Isotype: IgG

Information d'application

Indications d'application: Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Human

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur Osteocalcin

Antigène: Osteocalcin (BGLAP)

Autre désignation: BGLAP

Sujet:

Background: Osteocalcin, also known as bone gamma-carboxyglutamic acid-containing protein (BGLAP), is a noncollagenous protein found in bone and dentin. In humans, the osteocalcin is encoded by the BGLAP gene. Its receptor is GPRC6A. It is mapped to 1q22. Osteocalcin may play a role in the body's metabolic regulation and is pro-osteoblastic, or bone-building. It acts as a hormone in the body, causing beta cellsin the pancreas to release more insulin, and at the same time ing fat cells to release the hormone adiponectin, which increases sensitivity to insulin. Also, it may play a role in male fertility. And it is found that picomolar amounts of osteocalcin affected insulin secretion and beta-cell proliferation.

Gene Full Name: bone gamma-carboxyglutamate protein

Poids moléculaire: 29 kDa, 60 kDa

ID gène: 632

UniProt: P02818