Osteocalcin anticorps (AA 50-95) (HRP)
Aperçu rapide pour Osteocalcin anticorps (AA 50-95) (HRP) (ABIN8018508)
Antigène
Voir toutes Osteocalcin (BGLAP) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 50-95
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Fonction
- Anti-Osteocalcin/BGLAP Antibody HRP Conjugated
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Specificité
- No cross reactivity with other proteins.
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Réactivité croisée (Details)
- No cross-reactivity with other proteins
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Homologie
- coli-derived mouse Osteocalcin recombinant protein (Position: Y50-I95). Mouse Osteocalcin shares 69%,68.9% amino acid (aa) sequence identity with human,rat Osteocalcin,respectively.
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Purification
- Immunogen affinity purified.
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Immunogène
- E. coli-derived mouse Osteocalcin recombinant protein (Position: Y50-I95). Mouse Osteocalcin shares 69% and 68.9% amino acid (aa) sequence identity with human and rat Osteocalcin, respectively.
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Isotype
- IgG
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Indications d'application
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
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Stock
- -20 °C
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Stockage commentaire
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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Date de péremption
- 12 months
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- Osteocalcin (BGLAP)
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Autre désignation
- Bglap
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Sujet
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Background: Osteocalcin, also known as bone gamma-carboxyglutamic acid-containing protein (BGLAP), is a noncollagenous protein found in bone and dentin. In humans, the osteocalcin is encoded by the BGLAP gene. Its receptor is GPRC6A. It is mapped to 1q22. Osteocalcin may play a role in the body's metabolic regulation and is pro-osteoblastic, or bone-building. It acts as a hormone in the body, causing beta cellsin the pancreas to release more insulin, and at the same time ing fat cells to release the hormone adiponectin, which increases sensitivity to insulin. Also, it may play a role in male fertility. And it is found that picomolar amounts of osteocalcin affected insulin secretion and beta-cell proliferation.
Gene Full Name: bone gamma carboxyglutamate protein
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ID gène
- 12096
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UniProt
- P86546
Antigène
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