Osteocalcin anticorps (AA 50-99)
Aperçu rapide pour Osteocalcin anticorps (AA 50-99) (ABIN8018523)
Antigène
Voir toutes Osteocalcin (BGLAP) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
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Épitope
- AA 50-99
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Fonction
- Anti-Osteocalcin/BGLAP Antibody
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Specificité
- No cross reactivity with other proteins.
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Réactivité croisée (Details)
- No cross-reactivity with other proteins
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Homologie
- coli-derived rat Osteocalcin recombinant protein (Position: Y50-V99). Rat Osteocalcin shares 80.9%,68.9% amino acid (aa) sequence identity with human,mouse Osteocalcin,respectively.
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Attributs du produit
- Anti-Osteocalcin/BGLAP Antibody. Tested in Flow Cytometry, IHC applications. This antibody reacts with Rat.
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Purification
- Immunogen affinity purified.
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Immunogène
- E. coli-derived rat Osteocalcin recombinant protein (Position: Y50-V99). Rat Osteocalcin shares 80.9% and 68.9% amino acid (aa) sequence identity with human and mouse Osteocalcin, respectively.
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Isotype
- IgG
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Indications d'application
- Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Rat Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Rat
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles. -
Date de péremption
- 12 months
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- Osteocalcin (BGLAP)
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Autre désignation
- Bglap
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Sujet
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Background: Osteocalcin, also known as bone gamma-carboxyglutamic acid-containing protein (BGLAP), is a noncollagenous protein found in bone and dentin. In humans, the osteocalcin is encoded by the BGLAP gene. Its receptor is GPRC6A. It is mapped to 1q22. Osteocalcin may play a role in the body's metabolic regulation and is pro-osteoblastic, or bone-building. It acts as a hormone in the body, causing beta cellsin the pancreas to release more insulin, and at the same time ing fat cells to release the hormone adiponectin, which increases sensitivity to insulin. Also, it may play a role in male fertility. And it is found that picomolar amounts of osteocalcin affected insulin secretion and beta-cell proliferation.
Gene Full Name: bone gamma-carboxyglutamate protein
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Poids moléculaire
- 29 kDa, 60 kDa
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ID gène
- 25295
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UniProt
- P04640
Antigène
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