P-Cadherin anticorps (Middle Region) (HRP)

N° du produit ABIN8018937

L’anticorps anti-P-Cadherin Polyclonal Lapin est utilisé pour la détection de P-Cadherin dans des échantillons de Humain. Il a été validé pour WB, IHC et ELISA.

Aperçu rapide pour P-Cadherin anticorps (Middle Region) (HRP) (ABIN8018937)

Antigène: P-Cadherin (CDH3)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp P-Cadherin est conjugé à/à la HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-P-Cadherin anticorps (HRP)

Épitope: Middle Region

Fonction: Anti-P-Cadherin-3 CDH3-Antibody HRP Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: different from the mouse,rat sequences by one amino acid.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence in the middle region of human P cadherin, different from the mouse and rat sequences by one amino acid.

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur P-Cadherin

Antigène: P-Cadherin (CDH3)

Autre désignation: CDH3

Sujet:

Background: Cadherins, such as CDH3, are integral membrane glycoproteins responsible for calcium-dependent cell-cell adhesion. Cadherin-3 is a protein that in humans is encoded by the CDH3 gene. This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein composed of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. This gene is located in a six-cadherin cluster in a region on the long arm of chromosome 16 that is involved in loss of heterozygosity events in breast and prostate cancer. In addition, aberrant expression of this protein is observed in cervical adenocarcinomas. Mutations in this gene have been associated with congential hypotrichosis with juvenile macular dystrophy.

Gene Full Name: cadherin 3

Sequence Similarities: Contains 5 cadherin domains.

ID gène: 1001

UniProt: P22223