PAK7 anticorps (N-Term) (APC)

N° du produit ABIN8018949

L’anticorps anti-PAK7 Polyclonal Lapin est utilisé pour la détection de PAK7 dans des échantillons de Humain, Souris et Rat. Il a été validé pour FACS.

Aperçu rapide pour PAK7 anticorps (N-Term) (APC) (ABIN8018949)

Antigène: PAK7 (P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PAK7 est conjugé à/à la APC

Application: Flow Cytometry (FACS)

Détail du produit anti-PAK7 anticorps (APC)

Épitope: N-Term

Fonction: Anti-PAK5/PAK7 Antibody APC Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Homologie: identical to the related mouse,rat sequences.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human PAK5, identical to the related mouse and rat sequences.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur PAK7

Antigène: PAK7 (P21 Protein (Cdc42/Rac)-Activated Kinase 7 (PAK7))

Autre désignation: PAK5

Sujet:

Background: Serine/threonine-protein kinase PAK 7, also known as PAK5, is an enzyme that in humans is encoded by the PAK7 gene. The protein encoded by this gene is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling. This kinase contains a CDC42/Rac1 interactive binding (CRIB) motif, and has been shown to bind CDC42 in the presence of GTP. And this kinase is predominantly expressed in brain. It is capable of promoting neurite outgrowth, and thus may play a role in neurite development. In addition, this kinase is associated with microtubule networks and induces microtubule stabilization. The subcellular localization of this kinase is tightly regulated during cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described.

Gene Full Name: p21 (RAC1) activated kinase 5

ID gène: 57144

UniProt: Q9P286