Paired Box 3 anticorps (AA 306-420) (HRP)

N° du produit ABIN8019091

Cet anticorps anti-Paired Box 3 Polyclonal Lapin conjugué à HRP (ABIN8019091) détecte spécifiquement Paired Box 3 dans WB, ELISA et IHC. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Paired Box 3 anticorps (AA 306-420) (HRP) (ABIN8019091)

Antigène: Paired Box 3 (PAX3)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Paired Box 3 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-Paired Box 3 anticorps (HRP)

Épitope: AA 306-420

Fonction: Anti-PAX3 Antibody HRP Conjugated

Réactivité croisée (Details): No cross reactivity with other proteins.

Homologie: Human PAX3 shares 99.1% amino acid (aa) sequence identity with mouse PAX3.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human PAX3 recombinant protein (Position: Q306-E420). Human PAX3 shares 99.1% amino acid (aa) sequence identity with mouse PAX3.

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur Paired Box 3

Antigène: Paired Box 3 (PAX3)

Autre désignation: PAX3

Sujet:

Background: The PAX3 (paired box gene 3) gene encodes a member of the paired box or PAX family of transcription factors. This gene is a member of the paired box (PAX) family of transcription factors. Members of the PAX family typically contain a paired box domain and a paired-type homeodomain. These genes play critical roles during fetal development. Mutations in paired box gene 3 are associated with Waardenburg syndrome, craniofacial-deafness-hand syndrome, and alveolar rhabdomyosarcoma. The translocation t(2,13)(q35,q14), which represents a fusion between PAX3 and the forkhead gene, is a frequent finding in alveolar rhabdomyosarcoma. Alternative splicing results in transcripts encoding isoforms with different C-termini.

Gene Full Name: paired box 3

ID gène: 5077

UniProt: P23760

Pathways: Sensory Perception of Sound, Tube Formation