PITX2 anticorps (N-Term)

N° du produit ABIN8019228

L’anticorps anti-PITX2 Polyclonal Lapin est utilisé pour la détection de PITX2 dans des échantillons de Humain, Rat et Souris. Il a été validé pour WB et FACS.

Aperçu rapide pour PITX2 anticorps (N-Term) (ABIN8019228)

Antigène: PITX2 (Paired-Like Homeodomain 2 (PITX2))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PITX2 est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS)

Classe de qualité: Carrier-free

Détail du produit anti-PITX2 anticorps

Épitope: N-Term

Fonction: Anti-PITX2/RGS Antibody

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Homologie: identical to the related mouse,rat sequences.

Attributs du produit: Anti-PITX2/RGS Antibody. Tested in Flow Cytometry, WB applications. This antibody reacts with Mouse.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human PITX2/RGS, identical to the related mouse and rat sequences.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur PITX2

Antigène: PITX2 (Paired-Like Homeodomain 2 (PITX2))

Autre désignation: PITX2

Sujet:

Background: Paired-like homeodomain transcription factor 2?also known as?pituitary homeobox 2?is a?protein?that in humans is encoded by the?PITX2?gene. It is mapped to 4q25. This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. The encoded protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression. This protein plays a role in the terminal differentiation of somatotroph and lactotroph cell phenotypes, is involved in the development of the eye, tooth and abdominal organs, and acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin. Mutations in this gene are associated with Axenfeld-Rieger syndrome, iridogoniodysgenesis syndrome, and sporadic cases of Peters anomaly. A similar protein in other vertebrates is involved in the determination of left-right asymmetry during development. Alternatively spliced transcript variants encoding distinct isoforms have been described.

Gene Full Name: paired like homeodomain 2

Poids moléculaire: 35 kDa

ID gène: 5308

UniProt: Q99697

Pathways: Retinoic Acid Receptor Signaling Pathway, Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development