PON1 anticorps (AA 30-274) (HRP)
Aperçu rapide pour PON1 anticorps (AA 30-274) (HRP) (ABIN8019532)
Antigène
Voir toutes PON1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 30-274
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Fonction
- Anti-PON1 Antibody HRP Conjugated
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Specificité
- No cross reactivity with other proteins.
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Réactivité croisée (Details)
- No cross-reactivity with other proteins.
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Purification
- Immunogen affinity purified.
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Immunogène
- E. coli-derived rat PON1 recombinant protein (Position: A30-D274).
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Isotype
- IgG
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Indications d'application
- Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.
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Stock
- -20 °C
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Stockage commentaire
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.
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Date de péremption
- 12 months
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- PON1 (Paraoxonase 1 (PON1))
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Autre désignation
- Pon1
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Sujet
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Background: Serum paraoxonase/arylesterase 1 (PON1), also known as aromatic esterase 1, is an enzyme that in humans is encoded by the PON1 gene. It is mapped to 7q21.3. This gene has esterase and more specifically paraoxonase activity. PON1 is responsible for hydrolysing organophosphate pesticides and nerve gasses. Polymorphisms in the PON1 gene significantly affect the catalytic ability of the enzyme. PON1 (paraoxonase 1) is also a major anti-atherosclerotic component of high-density lipoprotein (HDL). The PON1 gene is activated by PPAR-γ, which increases synthesis and release of paraoxonase 1 enzyme from the liver, reducing atherosclerosis.
Gene Full Name: paraoxonase 1
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ID gène
- 84024
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UniProt
- P55159
Antigène
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