PON1 anticorps (Middle Region) (Cy3)

N° du produit ABIN8019549

L’anticorps anti-PON1 Polyclonal Lapin est utilisé pour la détection de PON1 dans des échantillons de Humain, Souris et Rat. Il a été validé pour FACS.

Aperçu rapide pour PON1 anticorps (Middle Region) (Cy3) (ABIN8019549)

Antigène: PON1 (Paraoxonase 1 (PON1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PON1 est conjugé à/à la Cy3

Application: Flow Cytometry (FACS)

Détail du produit anti-PON1 anticorps (Cy3)

Épitope: Middle Region

Fonction: Anti-PON1 Antibody Cy3 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: different from the related mouse,rat sequences by three amino acids.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence in the middle region of human PON1, different from the related mouse and rat sequences by three amino acids.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur PON1

Antigène: PON1 (Paraoxonase 1 (PON1))

Autre désignation: PON1

Sujet:

Background: Serum paraoxonase/arylesterase 1 (PON1), also known as aromatic esterase 1, is an enzyme that in humans is encoded by the PON1 gene. It is mapped to 7q21.3. This gene has esterase and more specifically paraoxonase activity. PON1 is responsible for hydrolysing organophosphate pesticides and nerve gasses. Polymorphisms in the PON1 gene significantly affect the catalytic ability of the enzyme. PON1 (paraoxonase 1) is also a major anti-atherosclerotic component of high-density lipoprotein (HDL). The PON1 gene is activated by PPAR-gamma, which increases synthesis and release of paraoxonase 1 enzyme from the liver, reducing atherosclerosis.

Gene Full Name: paraoxonase 1

Sequence Similarities: Belongs to the paraoxonase family.

ID gène: 5444

UniProt: P27169