PEG3 anticorps (AA 1-1548) (HRP)

N° du produit ABIN8019786

L’anticorps anti-PEG3 Polyclonal Lapin est utilisé pour la détection de PEG3 dans des échantillons de Humain. Il a été validé pour WB, ELISA et IHC.

Aperçu rapide pour PEG3 anticorps (AA 1-1548) (HRP) (ABIN8019786)

Antigène: PEG3 (Paternally Expressed 3 (PEG3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PEG3 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-PEG3 anticorps (HRP)

Épitope: AA 1-1548

Fonction: Anti-PEG3 Antibody HRP Conjugated

Réactivité croisée (Details): No cross reactivity with other proteins.

Homologie: Human PEG3 shares 62.3% amino acid (aa) sequence identity with mouse PEG3.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human PEG3 recombinant protein (Position: M1-R1548). Human PEG3 shares 62.3% amino acid (aa) sequence identity with mouse PEG3.

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur PEG3

Antigène: PEG3 (Paternally Expressed 3 (PEG3))

Autre désignation: PEG3

Sujet:

Background: Paternally-expressed gene 3 protein is a protein that in humans is encoded by the PEG3 gene. In human, ZIM2 and PEG3 are treated as two distinct genes though they share multiple 5' exons and a common promoter and both genes are paternally expressed (PMID:15203203). Alternative splicing events connect their shared 5' exons either with the remaining 4 exons unique to ZIM2, or with the remaining 2 exons unique to PEG3. In contrast, in other mammals ZIM2 does not undergo imprinting and, in mouse, cow, and likely other mammals as well, the ZIM2 and PEG3 genes do not share exons. Human PEG3 protein belongs to the Kruppel C2H2-type zinc finger protein family. PEG3 may play a role in cell proliferation and p53-mediated apoptosis. PEG3 has also shown tumor suppressor activity and tumorigenesis in glioma and ovarian cells. Alternative splicing of this PEG3 gene results in multiple transcript variants encoding distinct isoforms.

Gene Full Name: paternally expressed 3

ID gène: 5178

UniProt: Q9GZU2