PBK anticorps (AA 71-322) (FITC)

N° du produit ABIN8019966

L’anticorps anti-PBK Polyclonal Lapin est utilisé pour la détection de PBK dans des échantillons de Humain, Souris et Rat. Il a été validé pour FACS.

Aperçu rapide pour PBK anticorps (AA 71-322) (FITC) (ABIN8019966)

Antigène: PBK (PDZ Binding Kinase (PBK))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PBK est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Détail du produit anti-PBK anticorps (FITC)

Épitope: AA 71-322

Fonction: Anti-PBK Antibody FITC Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human PBK shares 89% amino acid (aa) sequence identity with mouse PBK.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human PBK recombinant protein (Position: N71-V322). Human PBK shares 89% amino acid (aa) sequence identity with mouse PBK.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur PBK

Antigène: PBK (PDZ Binding Kinase (PBK))

Autre désignation: PBK

Sujet:

Background: Lymphokine-activated killer T-cell-originated protein kinase, also known as TOPK or PBK, is an enzyme that in humans is encoded by the PBK gene. The protein encoded by this gene is a serine/threonine kinase related to the dual specific mitogen-activated protein kinase kinase (MAPKK) family. It is mapped to 8p21.1. PBK can mediate cell growth through histone H3 modification. Evidence suggests that mitotic phosphorylation is required for its catalytic activity. The encoded protein may be involved in the activation of lymphoid cells and support testicular functions, with a suggested role in the process of spermatogenesis. Overexpression of this gene has been implicated in tumorigenesis.

Gene Full Name: PDZ binding kinase

Sequence Similarities: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.

ID gène: 55872

UniProt: Q96KB5