PGC anticorps (AA 145-356) (FITC)

N° du produit ABIN8020078

Cet anticorps anti-PGC Polyclonal Lapin conjugué à FITC (ABIN8020078) détecte spécifiquement PGC dans FACS. L’anticorps est réactif avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour PGC anticorps (AA 145-356) (FITC) (ABIN8020078)

Antigène: PGC (Pepsinogen C (PGC))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PGC est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Détail du produit anti-PGC anticorps (FITC)

Épitope: AA 145-356

Fonction: Anti-PGC Antibody FITC Conjugated

Réactivité croisée (Details): No cross reactivity with other proteins.

Homologie: Human PGC shares 69.5%,70% amino acid (aa) sequence identity with mouse,rat PGC,respectively.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human PGC recombinant protein (Position: Y145-N356). Human PGC shares 69.5% and 70% amino acid (aa) sequence identity with mouse and rat PGC, respectively.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur PGC

Antigène: PGC (Pepsinogen C (PGC))

Autre désignation: PGC

Sujet:

Background: Progastricsin also known as pepsinogen C or pepsinogen II is a pepsinogen precursor of the enzyme gastricsin that in humans is encoded by the PGC gene. This gene encodes an aspartic proteinase that belongs to the peptidase family A1. The encoded protein is a digestive enzyme that is produced in the stomach and constitutes a major component of the gastric mucosa. This protein is also secreted into the serum. This protein is synthesized as an inactive zymogen that includes a highly basic prosegment. This enzyme is converted into its active mature form at low pH by sequential cleavage of the prosegment that is carried out by the enzyme itself. Polymorphisms in this gene are associated with susceptibility to gastric cancers. Serum levels of this enzyme are used as a biomarker for certain gastric diseases including Helicobacter pylori related gastritis. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 1.

Gene Full Name: progastricsin

ID gène: 5225

UniProt: P20142