PHF8 anticorps (AA 108-946) (Fluoro550)

N° du produit ABIN8021046

L’anticorps anti-PHF8 Polyclonal Lapin est utilisé pour la détection de PHF8 dans des échantillons de Humain. Il a été validé pour FACS.

Aperçu rapide pour PHF8 anticorps (AA 108-946) (Fluoro550) (ABIN8021046)

Antigène: PHF8 (PHD Finger Protein 8 (PHF8))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PHF8 est conjugé à/à la Fluoro550

Application: Flow Cytometry (FACS)

Détail du produit anti-PHF8 anticorps (Fluoro550)

Épitope: AA 108-946

Fonction: Anti-PHF8 Antibody Fluoro550 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human PHF8 shares 94.6% amino acid (aa) sequence identity with mouse PHF8.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human PHF8 recombinant protein (Position: H108-D946). Human PHF8 shares 94.6% amino acid (aa) sequence identity with mouse PHF8.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur PHF8

Antigène: PHF8 (PHD Finger Protein 8 (PHF8))

Autre désignation: PHF8

Sujet:

Background: The protein encoded by this gene is a histone lysine demethylase that preferentially acts on histones in the monomethyl or dimethyl states. The encoded protein requires Fe(2+) ion, 2-oxoglutarate, and oxygen for its catalytic activity. The protein has an N-terminal PHD finger and a central Jumonji C domain. This gene is thought to function as a transcription activator. Defects in this gene are a cause of syndromic X-linked Siderius type intellectual disability (MRXSSD) and over-expression of this gene is associated with several forms of cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: PHD finger protein 8

ID gène: 23133

UniProt: Q9UPP1