PHF8 anticorps (AA 108-946)

N° du produit ABIN8021053

Cet anticorps anti-PHF8 Polyclonal Lapin (ABIN8021053) détecte spécifiquement PHF8 dans WB, ICC, FACS, IF et ELISA. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour PHF8 anticorps (AA 108-946) (ABIN8021053)

Antigène: PHF8 (PHD Finger Protein 8 (PHF8))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PHF8 est non-conjugé

Application: Western Blotting (WB), Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunofluorescence (IF), ELISA

Classe de qualité: Carrier-free

Détail du produit anti-PHF8 anticorps

Épitope: AA 108-946

Fonction: Anti-PHF8 Antibody

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human PHF8 shares 94.6% amino acid (aa) sequence identity with mouse PHF8.

Attributs du produit: Anti-PHF8 Antibody. Tested in WB, ICC/IF, Flow Cytometry, ELISA applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human PHF8 recombinant protein (Position: H108-D946). Human PHF8 shares 94.6% amino acid (aa) sequence identity with mouse PHF8.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur PHF8

Antigène: PHF8 (PHD Finger Protein 8 (PHF8))

Autre désignation: PHF8

Sujet:

Background: The protein encoded by this gene is a histone lysine demethylase that preferentially acts on histones in the monomethyl or dimethyl states. The encoded protein requires Fe(2+) ion, 2-oxoglutarate, and oxygen for its catalytic activity. The protein has an N-terminal PHD finger and a central Jumonji C domain. This gene is thought to function as a transcription activator. Defects in this gene are a cause of syndromic X-linked Siderius type intellectual disability (MRXSSD) and over-expression of this gene is associated with several forms of cancer. Multiple transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: PHD finger protein 8

Poids moléculaire: 140 kDa

ID gène: 23133

UniProt: Q9UPP1