PDE8B anticorps (C-Term)
Aperçu rapide pour PDE8B anticorps (C-Term) (ABIN8021557)
Antigène
Voir toutes PDE8B AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- C-Term
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Fonction
- Anti-PDE8B Antibody
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Réactivité croisée (Details)
- No cross-reactivity with other proteins
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Homologie
- Human PDE8B shares 100% amino acid (aa) sequence identity with mouse PDE8B.
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Attributs du produit
- Anti-PDE8B Antibody. Tested in WB, ICC, IF applications. This antibody reacts with Human.
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Purification
- Immunogen affinity purified.
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Immunogène
- A synthetic peptide corresponding to a sequence at the C-terminus of human PDE8B. Human PDE8B shares 100% amino acid (aa) sequence identity with mouse PDE8B.
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Isotype
- IgG
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Indications d'application
- Western blot, 0.25-0.5 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
Date de péremption
- 12 months
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- PDE8B (phosphodiesterase 8B (PDE8B))
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Autre désignation
- PDE8B
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Sujet
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Background: The protein encoded by this gene is a cyclic nucleotide phosphodiesterase (PDE) that catalyzes the hydrolysis of the second messenger cAMP. The encoded protein, which does not hydrolyze cGMP, is resistant to several PDE inhibitors. Defects in this gene are a cause of autosomal dominant striatal degeneration (ADSD). Several transcript variants encoding different isoforms have been found for this gene.
Gene Full Name: phosphodiesterase 8B
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Poids moléculaire
- 99 kDa
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ID gène
- 8622
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UniProt
- O95263
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Pathways
- Negative Regulation of Hormone Secretion, cAMP Metabolic Process
Antigène
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