PDE8B anticorps (C-Term) (Biotin)

N° du produit ABIN8021558

Cet anticorps Lapin Polyclonal détecte spécifiquement PDE8B dans WB, ELISA et IHC. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour PDE8B anticorps (C-Term) (Biotin) (ABIN8021558)

Antigène: PDE8B (phosphodiesterase 8B (PDE8B))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PDE8B est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-PDE8B anticorps (Biotin)

Épitope: C-Term

Fonction: Anti-PDE8B Antibody Biotin Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human PDE8B shares 100% amino acid (aa) sequence identity with mouse PDE8B.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human PDE8B. Human PDE8B shares 100% amino acid (aa) sequence identity with mouse PDE8B.

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur PDE8B

Antigène: PDE8B (phosphodiesterase 8B (PDE8B))

Autre désignation: PDE8B

Sujet:

Background: The protein encoded by this gene is a cyclic nucleotide phosphodiesterase (PDE) that catalyzes the hydrolysis of the second messenger cAMP. The encoded protein, which does not hydrolyze cGMP, is resistant to several PDE inhibitors. Defects in this gene are a cause of autosomal dominant striatal degeneration (ADSD). Several transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: phosphodiesterase 8B

ID gène: 8622

UniProt: O95263

Pathways: Negative Regulation of Hormone Secretion, cAMP Metabolic Process