PLD1 anticorps (AA 1-330) (Biotin)

N° du produit ABIN8022213

L’anticorps anti-PLD1 Polyclonal Lapin est utilisé pour la détection de PLD1 dans des échantillons de Humain et Souris. Il a été validé pour ELISA, WB et IHC.

Aperçu rapide pour PLD1 anticorps (AA 1-330) (Biotin) (ABIN8022213)

Antigène: PLD1 (Phospholipase D1 (PLD1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PLD1 est conjugé à/à la Biotin

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC)

Détail du produit anti-PLD1 anticorps (Biotin)

Épitope: AA 1-330

Fonction: Anti-Phospholipase D1/PLD1 Antibody Biotin Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Homologie: Human PLD1 shares 91.8%,90.9% amino acid (aa) sequence identity with mouse,rat PLD1,respectively.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human PLD1 recombinant protein (Position: M1-H330). Human PLD1 shares 91.8% and 90.9% amino acid (aa) sequence identity with mouse and rat PLD1, respectively.

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur PLD1

Antigène: PLD1 (Phospholipase D1 (PLD1))

Autre désignation: PLD1

Sujet:

Background: By somatic cell hybrid analysis, PLD1 is mapped to 3q26.31. This gene encodes a phosphatidylcholine-specific phospholipase which catalyzes the hydrolysis of phosphatidylcholine in order to yield phosphatidic acid and choline. The enzyme may play a role in signal transduction and subcellular trafficking. Alternative splicing results in multiple transcript variants with both catalytic and regulatory properties. And PLD1 disrupted association of gamma-secretase protein components, independent of PLD1catalytic activity. What's more, PLD1 regulates intracellular trafficking of beta-amyloid, distinct from its effect on gamma-secretase activity.

Gene Full Name: phospholipase D1

Sequence Similarities: Belongs to the phospholipase D family.

ID gène: 5337

UniProt: Q13393