PLGF anticorps (AA 24-158)

N° du produit ABIN8022711

L’anticorps anti-PLGF Polyclonal Lapin est utilisé pour la détection de PLGF dans des échantillons de Souris et Rat. Il a été validé pour WB et ELISA.

Aperçu rapide pour PLGF anticorps (AA 24-158) (ABIN8022711)

Antigène: PLGF (PGF) (Placenta Growth Factor (PGF))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PLGF est non-conjugé

Application: Western Blotting (WB), ELISA

Classe de qualité: Carrier-free

Détail du produit anti-PLGF anticorps

Épitope: AA 24-158

Fonction: Anti-PGF Antibody

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-PGF Antibody. Tested in ELISA, WB applications. This antibody reacts with Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived rat PGF recombinant protein (Position: A24-L158).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL ELISA, 0.1-0.5 μg/mL

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur PLGF

Antigène: PLGF (PGF) (Placenta Growth Factor (PGF))

Autre désignation: Pgf

Sujet:

Background: Placental growth factor (PGF, also known as PLGF) codes for an angiogenic factor expressed in placental tissue that is similar to vascular permeability factor/vascular endothelial growth factor (VPF/VEGF). It is a glycosylated dimeric secreted protein able to stimulate endothelial cell growth in vitro. PGF is located on chromosome 14 and has been conserved in evolution. It belongs to the family of vascular endothelial growth factors (VEGFs) and binds to the flt-1 VEGF receptor. PLGF-2, which is a PLGF isoform, binds neuropilin-1 and 2 in a heparin-dependent manner. PGF regulates inter- and intra molecular cross talk between the VEGF RTKs Flt1 and Flk1 and stimulates the phosphorylation of specific Flt1 tyrosine residues and the expression of distinct downstream target genes. Moreover, it plays an important role in pathological angiogenic events and with exerting its biological activities through binding to VEGFR1.

Gene Full Name: placental growth factor

Poids moléculaire: 25 kDa

ID gène: 94203

UniProt: Q63434

Pathways: VEGFR1 Specific Signals