PLAU anticorps (AA 179-431) (Fluoro488)

N° du produit ABIN8022903

L’anticorps anti-PLAU Polyclonal Lapin est utilisé pour la détection de PLAU dans des échantillons de Humain, Souris et Rat. Il a été validé pour FACS.

Aperçu rapide pour PLAU anticorps (AA 179-431) (Fluoro488) (ABIN8022903)

Antigène: PLAU (Plasminogen Activator, Urokinase (PLAU))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PLAU est conjugé à/à la Fluoro488

Application: Flow Cytometry (FACS)

Détail du produit anti-PLAU anticorps (Fluoro488)

Épitope: AA 179-431

Fonction: Anti-PLAU Antibody Fluoro488 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived human PLAU recombinant protein (Position: I179-L431).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur PLAU

Antigène: PLAU (Plasminogen Activator, Urokinase (PLAU))

Autre désignation: PLAU

Sujet:

Background: Urokinase, also known as urokinase-type plasminogen activator (uPA), is a serine protease present in humans and other animals. This gene encodes a secreted serine protease that converts plasminogen to plasmin. The encoded preproprotein is proteolytically processed to generate A and B polypeptide chains. These chains associate via a single disulfide bond to form the catalytically inactive high molecular weight urokinase-type plasminogen activator (HMW-uPA). HMW-uPA can be further processed into the catalytically active low molecular weight urokinase-type plasminogen activator (LMW-uPA). This low molecular weight form does not bind to the urokinase-type plasminogen activator receptor. Mutations in this gene may be associated with Quebec platelet disorder and late-onset Alzheimer's disease. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

Gene Full Name: plasminogen activator, urokinase

ID gène: 5328

UniProt: P00749

Pathways: Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Autophagy, Smooth Muscle Cell Migration