PLAUR anticorps (AA 128-167)

N° du produit ABIN8022955

Cet anticorps anti-PLAUR Polyclonal Lapin (ABIN8022955) détecte spécifiquement PLAUR dans WB et ELISA. L’anticorps est réactif avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour PLAUR anticorps (AA 128-167) (ABIN8022955)

Antigène: PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PLAUR est non-conjugé

Application: Western Blotting (WB), ELISA

Classe de qualité: Carrier-free

Détail du produit anti-PLAUR anticorps

Épitope: AA 128-167

Fonction: Anti-uPA Receptor/U-PAR/PLAUR Antibody

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-uPA Receptor/U-PAR/PLAUR Antibody. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human uPA Receptor/U-PAR/PLAUR recombinant protein (Position: E128-R167).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human, Mouse, Rat ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur PLAUR

Antigène: PLAUR (Plasminogen Activator, Urokinase Receptor (PLAUR))

Autre désignation: PLAUR

Sujet:

Background: PLAUR(PLASMINOGEN ACTIVATOR RECEPTOR, UROKINASE-TYPE), also known as UPAR or CD87, is multidomain glycoprotein tethered to the cell membrane with a glycosylphosphotidylinositol (GPI) anchor. PLAUR consists of three different domains of the Ly-6/uPAR/alpha-neurotoxin family. PLAUR is originally identified as a saturable binding site for urokinase on the cell surface. And the gene plays an important role in many normal as well as pathologic processes. The PLAUR gene is localized to 19q13.31. PLAUR is a part of the plasminogen activation system, which in the healthy body is involved in tissue reorganization events such as mammary gland involution and wound healing. PLAUR binds urokinase and thus restricts plasminogen activation to the immediate vicinity of the cell membrane. Thus it seems to be an important player in the regulation of this process. In human coronary artery vascular smooth muscle cells, UPA stimulates cell migration via a UPAR signaling complex containing TYK2 and phosphatidylinositol 3-kinase.

Gene Full Name: plasminogen activator, urokinase receptor

Poids moléculaire: 45 kDa

ID gène: 5329

UniProt: Q03405

Pathways: Inositol Metabolic Process