PF4 anticorps (AA 30-105) (HRP)

N° du produit ABIN8023095

L’anticorps anti-PF4 Polyclonal Lapin est utilisé pour la détection de PF4 dans des échantillons de Souris. Il a été validé pour WB, IHC et ELISA.

Aperçu rapide pour PF4 anticorps (AA 30-105) (HRP) (ABIN8023095)

Antigène: PF4 (Platelet Factor 4 (PF4))

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PF4 est conjugé à/à la HRP

Application: Western Blotting (WB), Immunohistochemistry (IHC), ELISA

Détail du produit anti-PF4 anticorps (HRP)

Épitope: AA 30-105

Fonction: Anti-PF4 Antibody HRP Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: coli-derived mouse PF4 recombinant protein (Position: V30-S105). Mouse PF4 shares 74.3%,86.8% amino acid (aa) sequence identity with human,rat PF4,respectively.

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived mouse PF4 recombinant protein (Position: V30-S105). Mouse PF4 shares 74.3% and 86.8% amino acid (aa) sequence identity with human and rat PF4, respectively.

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur PF4

Antigène: PF4 (Platelet Factor 4 (PF4))

Autre désignation: Pf4

Sujet:

Background: Platelet factor 4 (PF4) is a small cytokine belonging to the CXC chemokine family that is also known as chemokine (C-X-C motif) ligand 4 (CXCL4). By in situ hybridization, the CXCL4 gene is mapped to chromosome 4q12-q21. Its major physiologic role appears to be neutralization of heparin-like molecules on the endothelial surface of blood vessels, thereby inhibiting local antithrombin III activity and promoting coagulation. As a strong chemoattractant for neutrophils and fibroblasts, PF4 probably has a role in inflammation and wound repair.

Gene Full Name: platelet factor 4

Sequence Similarities: Belongs to the transient receptor (TC 1.A.4) family. STrpC subfamily. TRPC4 sub-subfamily.

ID gène: 56744

UniProt: Q9Z126