PABPN1 anticorps (Middle Region) (Fluoro488)

N° du produit ABIN8023889

Cet anticorps Lapin Polyclonal détecte spécifiquement PABPN1 dans FACS. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour PABPN1 anticorps (Middle Region) (Fluoro488) (ABIN8023889)

Antigène: PABPN1 (Poly A Binding Protein Nuclear 1 (PABPN1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PABPN1 est conjugé à/à la Fluoro488

Application: Flow Cytometry (FACS)

Détail du produit anti-PABPN1 anticorps (Fluoro488)

Épitope: Middle Region

Fonction: Anti-PABPN1 Antibody Fluoro488 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human PABPN1 shares 100% amino acid (aa) sequence identity with mouse PABPN1.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence in the middle region of human PABPN1. Human PABPN1 shares 100% amino acid (aa) sequence identity with mouse PABPN1.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur PABPN1

Antigène: PABPN1 (Poly A Binding Protein Nuclear 1 (PABPN1))

Autre désignation: PABPN1

Sujet:

Background: This gene encodes an abundant nuclear protein that binds with high affinity to nascent poly(A) tails. The protein is required for progressive and efficient polymerization of poly(A) tails at the 3' ends of eukaryotic transcripts and controls the size of the poly(A) tail to about 250 nt. At steady-state, this protein is localized in the nucleus whereas a different poly(A) binding protein is localized in the cytoplasm. This gene contains a GCG trinucleotide repeat at the 5' end of the coding region, and expansion of this repeat from the normal 6 copies to 8-13 copies leads to autosomal dominant oculopharyngeal muscular dystrophy (OPMD) disease. Related pseudogenes have been identified on chromosomes 19 and X. Read-through transcription also exists between this gene and the neighboring upstream BCL2-like 2 (BCL2L2) gene.

Gene Full Name: poly(A) binding protein nuclear 1

ID gène: 8106

UniProt: Q86U42