PKD2 anticorps (AA 829-893) (Biotin)

N° du produit ABIN8024031

L’anticorps anti-PKD2 Polyclonal Lapin est utilisé pour la détection de PKD2 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, ELISA et IHC.

Aperçu rapide pour PKD2 anticorps (AA 829-893) (Biotin) (ABIN8024031)

Antigène: PKD2 (Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PKD2 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-PKD2 anticorps (Biotin)

Épitope: AA 829-893

Fonction: Anti-Polycystin 2/PKD2 Antibody Biotin Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Polycystin 2/PKD2 recombinant protein (Position: S829-R893).

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur PKD2

Antigène: PKD2 (Polycystic Kidney Disease 2 (Autosomal Dominant) (PKD2))

Autre désignation: PKD2

Sujet:

Background: Polycystin-2?is a?protein?that in humans is encoded by the?PKD2?gene. It is mapped to 4q22.1. This gene encodes a member of the polycystin protein family. The encoded protein is a multi-pass membrane protein that functions as a calcium permeable cation channel, and is involved in calcium transport and calcium signaling in renal epithelial cells. This protein interacts with polycystin 1, and they may be partners in a common signaling cascade involved in tubular morphogenesis. Mutations in this gene are associated with autosomal dominant polycystic kidney disease type 2.

Gene Full Name: polycystin 2, transient receptor potential cation channel

ID gène: 5311

UniProt: Q13563

Pathways: cAMP Metabolic Process, Maintenance of Protein Location, Negative Regulation of Transporter Activity