PRDM8 anticorps (AA 14-405) (HRP)

N° du produit ABIN8025000

L’anticorps anti-PRDM8 Polyclonal Lapin est utilisé pour la détection de PRDM8 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, ELISA et IHC.

Aperçu rapide pour PRDM8 anticorps (AA 14-405) (HRP) (ABIN8025000)

Antigène: PRDM8 (PR Domain Containing 8 (PRDM8))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRDM8 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-PRDM8 anticorps (HRP)

Épitope: AA 14-405

Fonction: Anti-PRDM8 Antibody HRP Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human PRDM8 recombinant protein (Position: D14-D405).

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur PRDM8

Antigène: PRDM8 (PR Domain Containing 8 (PRDM8))

Autre désignation: PRDM8

Sujet:

Background: This gene encodes a protein that belongs to a conserved family of histone methyltransferases that predominantly act as negative regulators of transcription. The encoded protein contains an N-terminal Su(var)3-9, Enhancer-of-zeste, and Trithorax (SET) domain and a double zinc-finger domain. Knockout of this gene in mouse results in mistargeting by neurons of the dorsal telencephalon, abnormal itch-like behavior, and impaired differentiation of rod bipolar cells. In humans, the protein has been shown to interact with the phosphatase laforin and the ubiquitin ligase malin, which regulate glycogen construction in the cytoplasm. Alternative splicing results in multiple transcript variants.

Gene Full Name: PR/SET domain 8

ID gène: 56978

UniProt: Q9NQV8