PFN2 anticorps (AA 96-138) (FITC)

N° du produit ABIN8025412

Cet anticorps anti-PFN2 Polyclonal Lapin conjugué à FITC (ABIN8025412) détecte spécifiquement PFN2 dans FACS. L’anticorps est réactif avec des échantillons de Humain, Rat et Souris.

Aperçu rapide pour PFN2 anticorps (AA 96-138) (FITC) (ABIN8025412)

Antigène: PFN2 (Profilin 2 (PFN2))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PFN2 est conjugé à/à la FITC

Application: Flow Cytometry (FACS)

Détail du produit anti-PFN2 anticorps (FITC)

Épitope: AA 96-138

Fonction: Anti-Profilin 2/PFN2 Antibody FITC Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Profilin 2/PFN2 recombinant protein (Position: E96-S138).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur PFN2

Antigène: PFN2 (Profilin 2 (PFN2))

Autre désignation: PFN2

Sujet:

Background: Profilin-2, also called PFN2, is a protein that in humans is encoded by the PFN2 gene. The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. This gene is mapped to 3q25.1. It is though to regulate actin polymerization in response to extracellular signals. There are two alternatively spliced transcript variants encoding different isoforms described for this gene. It binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.

Gene Full Name: profilin 2

ID gène: 5217

UniProt: P35080

Pathways: Regulation of Actin Filament Polymerization, Synaptic Vesicle Exocytosis