PFN2 anticorps (C-Term) (Fluoro488)

N° du produit ABIN8025420

L’anticorps anti-PFN2 Polyclonal Lapin est utilisé pour la détection de PFN2 dans des échantillons de Humain, Rat et Souris. Il a été validé pour FACS.

Aperçu rapide pour PFN2 anticorps (C-Term) (Fluoro488) (ABIN8025420)

Antigène: PFN2 (Profilin 2 (PFN2))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PFN2 est conjugé à/à la Fluoro488

Application: Flow Cytometry (FACS)

Détail du produit anti-PFN2 anticorps (Fluoro488)

Épitope: C-Term

Fonction: Anti-Profilin 2/PFN2 Antibody Fluoro488 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: identical to the related mouse,rat sequences.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human Profilin 2, identical to the related mouse and rat sequences.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur PFN2

Antigène: PFN2 (Profilin 2 (PFN2))

Autre désignation: PFN2

Sujet:

Background: Profilin-2, also called PFN2, is a protein that in humans is encoded by the PFN2 gene. The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. This gene is mapped to 3q25.1. It is though to regulate actin polymerization in response to extracellular signals. There are two alternatively spliced transcript variants encoding different isoforms described for this gene. It binds to actin and affects the structure of the cytoskeleton. At high concentrations, profilin prevents the polymerization of actin, whereas it enhances it at low concentrations. By binding to PIP2, it inhibits the formation of IP3 and DG.

Gene Full Name: profilin 2

Sequence Similarities: Contains 17 laminin EGF-like domains.

ID gène: 5217

UniProt: P35080

Pathways: Regulation of Actin Filament Polymerization, Synaptic Vesicle Exocytosis