PRELP anticorps (AA 69-353)

N° du produit ABIN8025848

Cet anticorps Lapin Polyclonal détecte spécifiquement PRELP dans WB, FACS et ELISA. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour PRELP anticorps (AA 69-353) (ABIN8025848)

Antigène: PRELP (Proline Arginine Rich End Leucine Rich Repeat Protein (PRELP))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRELP est non-conjugé

Application: Western Blotting (WB), Flow Cytometry (FACS), ELISA

Classe de qualité: Carrier-free

Détail du produit anti-PRELP anticorps

Épitope: AA 69-353

Fonction: Anti-PRELP Antibody

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-PRELP Antibody. Tested in ELISA, WB, Flow Cytometry applications. This antibody reacts with Human, Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human PRELP recombinant protein (Position: I69-R353).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.25 μg/mL, Human, Mouse, Rat Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur PRELP

Antigène: PRELP (Proline Arginine Rich End Leucine Rich Repeat Protein (PRELP))

Autre désignation: PRELP

Sujet:

Background: Prolargin is a protein that in humans is encoded by the PRELP gene. The protein encoded by this gene is a leucine-rich repeat protein present in connective tissue extracellular matrix. This protein functions as a molecule anchoring basement membranes to the underlying connective tissue. This protein has been shown to bind type I collagen to basement membranes and type II collagen to cartilage. It also binds the basement membrane heparan sulfate proteoglycan perlecan. This protein is suggested to be involved in the pathogenesis of Hutchinson-Gilford progeria (HGP), which is reported to lack the binding of collagen in basement membranes and cartilage. Alternatively spliced transcript variants encoding the same protein have been observed.

Gene Full Name: proline and arginine rich end leucine rich repeat protein

Poids moléculaire: 65 kDa

ID gène: 5549

UniProt: P51888

Pathways: Glycosaminoglycan Metabolic Process