PKC eta anticorps (AA 30-389) (Fluoro647)

N° du produit ABIN8027507

Cet anticorps Lapin Polyclonal détecte spécifiquement PKC eta dans FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour PKC eta anticorps (AA 30-389) (Fluoro647) (ABIN8027507)

Antigène: PKC eta (PRKCH) (Protein Kinase C, eta (PRKCH))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PKC eta est conjugé à/à la Fluoro647

Application: Flow Cytometry (FACS)

Détail du produit anti-PKC eta anticorps (Fluoro647)

Épitope: AA 30-389

Fonction: Anti-PKC eta/PRKCH Antibody Fluoro647 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human PKC eta shares 96.7%,96.1% amino acid (aa) sequence identity with mouse,rat PKC eta,respectively.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human PKC eta recombinant protein (Position: R30-D389). Human PKC eta shares 96.7% and 96.1% amino acid (aa) sequence identity with mouse and rat PKC eta, respectively.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur PKC eta

Antigène: PKC eta (PRKCH) (Protein Kinase C, eta (PRKCH))

Autre désignation: PRKCH

Sujet:

Background: PRKCH is also known as PKC eta. Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. Also, PKC family members serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipids-dependent protein kinase. And it is predominantly expressed in epithelial tissues and has been shown to reside specifically in the cell nucleus. This protein kinase can regulate keratinocyte differentiation by activating the MAP kinase MAPK13 (p38delta)-activated protein kinase cascade that targets CCAAT/enhancer-binding protein alpha (CEBPA). It is also found to mediate the transcription activation of the transglutaminase 1 (TGM1) gene.

Gene Full Name: protein kinase C eta

Sequence Similarities: Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.

ID gène: 5583

UniProt: P24723

Pathways: Myometrial Relaxation and Contraction, Thromboxane A2 Receptor Signaling