PKDCC anticorps (AA 129-490)
Aperçu rapide pour PKDCC anticorps (AA 129-490) (ABIN8027575)
Antigène
Voir toutes PKDCC AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
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Épitope
- AA 129-490
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Fonction
- Anti-SGK493/PKDCC Antibody
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Réactivité croisée (Details)
- No cross reactivity with other proteins.
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Homologie
- Human PKDCC shares 93.4% amino acid (aa) sequence identity with mouse PKDCC.
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Attributs du produit
- Anti-SGK493/PKDCC Antibody. Tested in ELISA, IF, IHC, ICC, WB, Flow Cytometry applications. This antibody reacts with Human.
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Purification
- Immunogen affinity purified.
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Immunogène
- E.coli-derived human SGK493/PKDCC recombinant protein (Position: R129-K490). Human PKDCC shares 93.4% amino acid (aa) sequence identity with mouse PKDCC.
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Isotype
- IgG
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Indications d'application
- Western blot, 0.1-0.25 μg/mL, Human Immunohistochemistry (Paraffin-embedded Section), 1-2 μg/mL, Human Immunocytochemistry/Immunofluorescence, 5 μg/mL, Human Immunofluorescence, 5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
Date de péremption
- 12 months
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- PKDCC (Protein Kinase Domain Containing, Cytoplasmic Homolog (Mouse) (PKDCC))
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Autre désignation
- PKDCC
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Sujet
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Background: VLK was identified as a novel protein kinase that was induced after the differentiation of cultured embryonic stem cells into mesendoderm. It has no homologs in invertebrates, but is highly conserved in vertebrate species although it does not belong to any known protein kinase groups. VLK is initially expressed in E-cadherin-positive anterior visceral endoderm and mesendoderm, but its expression is later confined to E-cadherin-negative mesenchyme. It is enriched in the Golgi apparatus and is thought to regulate the rate of protein export from the Golgi. Targeted disruption of VLK in mice leads to a defect in lung development and neonatal lethality. It has been suggested that mutations in VLK may be associated with the allergic condition atopy.
Gene Full Name: protein kinase domain containing, cytoplasmic
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Poids moléculaire
- 54 kDa
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ID gène
- 91461
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UniProt
- Q504Y2
Antigène
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