PRC1 anticorps (AA 1-233) (Cy3)

N° du produit ABIN8028275

Cet anticorps Lapin Polyclonal détecte spécifiquement PRC1 dans FACS. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour PRC1 anticorps (AA 1-233) (Cy3) (ABIN8028275)

Antigène: PRC1 (Protein Regulator of Cytokinesis 1 (PRC1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRC1 est conjugé à/à la Cy3

Application: Flow Cytometry (FACS)

Détail du produit anti-PRC1 anticorps (Cy3)

Épitope: AA 1-233

Fonction: Anti-PRC1 Antibody Cy3 Conjugated

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins.

Homologie: Human PRC1 shares 85% amino acid (aa) sequence identity with mouse PRC1.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human PRC1 recombinant protein (Position: M1-E233). Human PRC1 shares 85% amino acid (aa) sequence identity with mouse PRC1.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, 1-3 μg/1x10⁶ cells

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur PRC1

Antigène: PRC1 (Protein Regulator of Cytokinesis 1 (PRC1))

Autre désignation: PRC1

Sujet:

Background: Protein Regulator of cytokinesis 1 (PRC1) is a protein that in humans is encoded by the PRC1 gene and is involved in cytokinesis. This gene is mapped to chromosome 15q26.1 based on an alignment of the PRC1 sequence with the genomic sequence. PRC1 protein is expressed at relatively high levels during S and G2/M phases of the cell cycle before dropping dramatically after mitotic exit and entrance into G1 phase. It is located in the nucleus during interphase, becomes associated with the mitotic spindle in a highly dynamic manner during anaphase, and localizes to the cell midbody during cytokinesis. And this protein has been shown to be a substrate of several cyclin-dependent kinases (CDKs). It is necessary for polarizing parallel microtubules and concentrating the factors responsible for contractile ring assembly. Alternative splicing results in multiple transcript variants.

Gene Full Name: protein regulator of cytokinesis 1

ID gène: 9055

UniProt: O43663