PCMT1 anticorps (AA 1-227) (HRP)

N° du produit ABIN8028577

Cet anticorps anti-PCMT1 Polyclonal Lapin conjugué à HRP (ABIN8028577) détecte spécifiquement PCMT1 dans WB, ELISA et IHC. L’anticorps est réactif avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour PCMT1 anticorps (AA 1-227) (HRP) (ABIN8028577)

Antigène: PCMT1 (Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PCMT1 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-PCMT1 anticorps (HRP)

Épitope: AA 1-227

Fonction: Anti-PCMT1 Antibody HRP Conjugated

Réactivité croisée (Details): No cross reactivity with other proteins.

Homologie: Human PCMT1 shares 96%,95.6% amino acid (aa) sequence identity with mouse,rat PCMT1,respectively.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human PCMT1 recombinant protein (Position: M1-K227). Human PCMT1 shares 96% and 95.6% amino acid (aa) sequence identity with mouse and rat PCMT1, respectively.

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur PCMT1

Antigène: PCMT1 (Protein-L-Isoaspartate (D-Aspartate) O-Methyltransferase (PCMT1))

Autre désignation: PCMT1

Sujet:

Background: Protein-L-isoaspartate(D-aspartate) O-methyltransferase is an enzyme that in humans is encoded by the PCMT1 gene. This gene encodes a member of the type II class of protein carboxyl methyltransferase enzymes. The encoded enzyme plays a role in protein repair by recognizing and converting D-aspartyl and L-isoaspartyl residues resulting from spontaneous deamidation back to the normal L-aspartyl form. The encoded protein may play a protective role in the pathogenesis of Alzheimer's disease, and single nucleotide polymorphisms in this gene have been associated with spina bifida and premature ovarian failure. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Gene Full Name: protein-L-isoaspartate (D-aspartate) O-methyltransferase

ID gène: 5110

UniProt: P22061

Pathways: Ribonucleoprotein Complex Subunit Organization