PCDHa13 anticorps (AA 165-349) (Biotin)

N° du produit ABIN8028681

L’anticorps anti-PCDHa13 Polyclonal Lapin est utilisé pour la détection de PCDHa13 dans des échantillons de Humain. Il a été validé pour WB, ELISA et IHC.

Aperçu rapide pour PCDHa13 anticorps (AA 165-349) (Biotin) (ABIN8028681)

Antigène: PCDHa13 (Protocadherin alpha 13 (PCDHa13))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PCDHa13 est conjugé à/à la Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-PCDHa13 anticorps (Biotin)

Épitope: AA 165-349

Fonction: Anti-PCDHA13 Antibody Biotin Conjugated

Réactivité croisée (Details): No cross reactivity with other proteins.

Homologie: Human PCDHA13 shares 58.9% amino acid (aa) sequence identity with mouse PCDHA13.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human PCDHA13 recombinant protein (Position: N165-E349). Human PCDHA13 shares 58.9% amino acid (aa) sequence identity with mouse PCDHA13.

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur PCDHa13

Antigène: PCDHa13 (Protocadherin alpha 13 (PCDHa13))

Autre désignation: PCDHA13

Sujet:

Background: This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined.

Gene Full Name: protocadherin alpha 13

ID gène: 56136

UniProt: Q9Y5I0