Protocadherin gamma Subfamily C, 3 (PCDHGC3) (AA 498-804) anticorps
Aperçu rapide pour Protocadherin gamma Subfamily C, 3 (PCDHGC3) (AA 498-804) anticorps (ABIN8028757)
Antigène
Voir toutes Protocadherin gamma Subfamily C, 3 (PCDHGC3) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Classe de qualité
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Épitope
- AA 498-804
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Fonction
- Anti-PCDHGC3 Antibody
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Réactivité croisée (Details)
- No cross reactivity with other proteins.
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Attributs du produit
- Anti-PCDHGC3 Antibody. Tested in ELISA, WB, Flow Cytometry applications. This antibody reacts with Human, Rat.
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Purification
- Immunogen affinity purified.
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Immunogène
- E.coli-derived human PCDHGC3 recombinant protein (Position: E498-E804).
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Isotype
- IgG
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Indications d'application
- Western blot, 0.25-0.5 μg/mL, Human, Rat Flow Cytometry (Fixed), 1-3 μg/1x106 cells, Human ELISA, 0.1-0.5 μg/mL, -
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing. -
Date de péremption
- 12 months
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- Protocadherin gamma Subfamily C, 3 (PCDHGC3)
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Autre désignation
- PCDHGC3
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Sujet
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Background: Protocadherin gamma-C3 is a protein that in humans is encoded by the PCDHGC3 gene. This gene is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
Gene Full Name: protocadherin gamma subfamily C, 3
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Poids moléculaire
- 118 kDa
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ID gène
- 5098
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UniProt
- Q9UN70
Antigène
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