RAD51AP1 anticorps (AA 1-303) (HRP)

N° du produit ABIN8030123

Cet anticorps Lapin Polyclonal détecte spécifiquement RAD51AP1 dans WB, ELISA et IHC. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour RAD51AP1 anticorps (AA 1-303) (HRP) (ABIN8030123)

Antigène: RAD51AP1 (RAD51-Interacting Protein (RAD51AP1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAD51AP1 est conjugé à/à la HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit anti-RAD51AP1 anticorps (HRP)

Épitope: AA 1-303

Fonction: Anti-RAD51AP1 Antibody HRP Conjugated

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human RAD51AP1 recombinant protein (Position: M1-K303).

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur RAD51AP1

Antigène: RAD51AP1 (RAD51-Interacting Protein (RAD51AP1))

Autre désignation: RAD51AP1

Sujet:

Background: The RAD51AP1 gene encodes a protein known as RAD51-associated protein 1, which plays a crucial role in homologous recombination, a DNA repair pathway essential for maintaining genomic integrity. RAD51AP1 interacts with RAD51, a key protein involved in homologous recombination, and promotes the assembly of RAD51 nucleoprotein filaments on single-stranded DNA, facilitating the search for homologous sequences and strand exchange. This process is vital for repairing DNA double-strand breaks and stalled replication forks, as well as for meiotic recombination and telomere maintenance. Dysregulation of RAD51AP1 expression or function has been implicated in cancer development and progression, as defects in homologous recombination can lead to genomic instability and oncogenesis. Understanding the molecular mechanisms underlying RAD51AP1-mediated homologous recombination is crucial for deciphering its role in DNA repair and genome maintenance, as well as for developing targeted therapies for cancer and other diseases associated with DNA damage.

Gene Full Name: RAD51 associated protein 1

ID gène: 10635

UniProt: Q96B01