RASD1 anticorps (AA 1-281) (Fluoro647)

N° du produit ABIN8030813

Cet anticorps Lapin Polyclonal détecte spécifiquement RASD1 dans FACS. Il présente une réactivité avec des échantillons de Souris, Humain et Rat.

Aperçu rapide pour RASD1 anticorps (AA 1-281) (Fluoro647) (ABIN8030813)

Antigène: RASD1 (RAS, Dexamethasone-Induced 1 (RASD1))

Reactivité: Souris, Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RASD1 est conjugé à/à la Fluoro647

Application: Flow Cytometry (FACS)

Détail du produit anti-RASD1 anticorps (Fluoro647)

Épitope: AA 1-281

Fonction: Anti-Dexras1/RASD1 Antibody Fluoro647 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human Dexras1/RASD1 recombinant protein (Position: M1-S281).

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur RASD1

Antigène: RASD1 (RAS, Dexamethasone-Induced 1 (RASD1))

Autre désignation: RASD1

Sujet:

Background: Dexamethasone-induced Ras-related protein 1 (RASD1) is a protein that in humans is encoded by the RASD1 gene on chromosome 17. This gene encodes a member of the Ras superfamily of small GTPases and is induced by dexamethasone. The encoded protein is an activator of G-protein signaling and acts as a nucleotide exchange factor for Gi-Go proteins. This protein interacts with the neuronal nitric oxide adaptor protein CAPON, and a nuclear adaptor protein FE65, which interacts with the Alzheimer's disease amyloid precursor protein. This gene may play a role in dexamethasone-induced alterations in cell morphology, growth and cell-extracellular matrix interactions. Epigenetic inactivation of this gene is closely correlated with resistance to dexamethasone in multiple myeloma cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Full Name: ras related dexamethasone induced 1

ID gène: 51655

UniProt: Q9Y272