REST anticorps (AA 110-1097) (Cy3)

N° du produit ABIN8030838

L’anticorps anti-REST Polyclonal Lapin est utilisé pour la détection de REST dans des échantillons de Humain. Il a été validé pour FACS.

Aperçu rapide pour REST anticorps (AA 110-1097) (Cy3) (ABIN8030838)

Antigène: REST (RE1-Silencing Transcription Factor (REST))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp REST est conjugé à/à la Cy3

Application: Flow Cytometry (FACS)

Détail du produit anti-REST anticorps (Cy3)

Épitope: AA 110-1097

Fonction: Anti-REST Antibody Cy3 Conjugated

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: Human REST shares 62.9%,59.6% amino acid (aa) sequence identity with mouse,rat REST,respectively.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human REST recombinant protein (Position: E110-E1097). Human REST shares 62.9% and 59.6% amino acid (aa) sequence identity with mouse and rat REST, respectively.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur REST

Antigène: REST (RE1-Silencing Transcription Factor (REST))

Autre désignation: REST

Sujet:

Background: This gene was initially identified as a transcriptional repressor that represses neuronal genes in non-neuronal tissues. However, depending on the cellular context, this gene can act as either an oncogene or a tumor suppressor. The encoded protein is a member of the Kruppel-type zinc finger transcription factor family. It represses transcription by binding a DNA sequence element called the neuron-restrictive silencer element. The protein is also found in undifferentiated neuronal progenitor cells and it is thought that this repressor may act as a master negative regulator of neurogenesis. Alternatively spliced transcript variants have been described.

Gene Full Name: RE1 silencing transcription factor

ID gène: 5978

UniProt: Q13127

Pathways: Negative Regulation of Hormone Secretion, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, Chromatin Binding, Positive Regulation of Endopeptidase Activity