Replication Termination Factor 2 (RTF2) (AA 4-306) anticorps (HRP)

N° du produit ABIN8031603

L’anticorps anti-Replication Termination Factor 2 Polyclonal Lapin est utilisé pour la détection de Replication Termination Factor 2 dans des échantillons de Humain. Il a été validé pour WB, ELISA et IHC.

Aperçu rapide pour Replication Termination Factor 2 (RTF2) (AA 4-306) anticorps (HRP) (ABIN8031603)

Antigène: Replication Termination Factor 2 (RTF2)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Détail du produit

Épitope: AA 4-306

Fonction: Anti-RTF2 Antibody HRP Conjugated

Homologie: Human RTF2 shares 87.8%,88.1% amino acid (aa) sequence identity with mouse,rat RTF2,respectively.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human RTF2 recombinant protein (Position: D4-F306). Human RTF2 shares 87.8% and 88.1% amino acid (aa) sequence identity with mouse and rat RTF2, respectively.

Isotype: IgG

Information d'application

Indications d'application: Western blot, Optimal dilutions should be determined by end users. Immunohistochemistry (Paraffin-embedded Section), Optimal dilutions should be determined by end users. ELISA, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détail du antigène

Antigène: Replication Termination Factor 2 (RTF2)

Autre désignation: RTF2

Sujet:

Background: Replication termination factor 2 is a protein that in humans is encoded by the RTF2 gene. Replication Termination Factor 2, often abbreviated as RTF2, is a protein involved in the regulation and termination of DNA replication processes in eukaryotic cells. It plays a crucial role in ensuring the accurate completion of DNA synthesis during cell division by coordinating the termination of replication forks at specific sites along the DNA strands. RTF2 functions by interacting with other proteins and DNA sequences to facilitate the orderly disassembly of the replication machinery and the prevention of unnecessary re-replication of genomic regions. Its activity is tightly regulated to maintain genomic stability and fidelity, making it a key player in cell cycle control mechanisms. Studies on RTF2 have provided insights into the molecular mechanisms governing DNA replication termination and its implications for cellular function and genome maintenance.

Gene Full Name: replication termination factor 2

ID gène: 51507

UniProt: Q9BY42