Rhotekin anticorps (AA 255-554) (Cy3)
Aperçu rapide pour Rhotekin anticorps (AA 255-554) (Cy3) (ABIN8032283)
Antigène
Voir toutes Rhotekin (RTKN) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 255-554
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Fonction
- Anti-RTKN Antibody Cy3 Conjugated
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Réactivité croisée (Details)
- No cross-reactivity with other proteins.
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Purification
- Immunogen affinity purified.
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Immunogène
- E.coli-derived human RTKN recombinant protein (Position: R255-Q554).
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Isotype
- IgG
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Indications d'application
- Flow Cytometry, 1-3 μg/1x106 cells
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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Date de péremption
- 12 months
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- Rhotekin (RTKN)
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Autre désignation
- RTKN
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Sujet
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Background: Rhotekin is a protein that in humans is encoded by the RTKN gene. This gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth and transformation. Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.
Gene Full Name: rhotekin
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ID gène
- 6242
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UniProt
- Q9BST9
Antigène
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