Rhotekin anticorps (AA 255-554)

N° du produit ABIN8032292

Cet anticorps Lapin Polyclonal détecte spécifiquement Rhotekin dans WB, ELISA et FACS. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour Rhotekin anticorps (AA 255-554) (ABIN8032292)

Antigène: Rhotekin (RTKN)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Rhotekin est non-conjugé

Application: Western Blotting (WB), ELISA, Flow Cytometry (FACS)

Classe de qualité: Carrier-free

Détail du produit anti-Rhotekin anticorps

Épitope: AA 255-554

Fonction: Anti-RTKN Antibody

Réactivité croisée (Details): No cross-reactivity with other proteins.

Attributs du produit: Anti-RTKN Antibody. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human RTKN recombinant protein (Position: R255-Q554).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.25-0.5 μg/mL, Human Flow Cytometry (Fixed), 1-3 μg/1x10⁶ cells, Human ELISA, 0.1-0.5 μg/mL, -

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Adding 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4.

Stock: 4 °C,-20 °C

Stockage commentaire: At -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur Rhotekin

Antigène: Rhotekin (RTKN)

Autre désignation: RTKN

Sujet:

Background: Rhotekin is a protein that in humans is encoded by the RTKN gene. This gene encodes a scaffold protein that interacts with GTP-bound Rho proteins. Binding of this protein inhibits the GTPase activity of Rho proteins. This protein may interfere with the conversion of active, GTP-bound Rho to the inactive GDP-bound form by RhoGAP. Rho proteins regulate many important cellular processes, including cytokinesis, transcription, smooth muscle contraction, cell growth and transformation. Dysregulation of the Rho signal transduction pathway has been implicated in many forms of cancer. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene Full Name: rhotekin

Poids moléculaire: 70 kDa

ID gène: 6242

UniProt: Q9BST9