RTKN2 anticorps (AA 1-572) (PE)

N° du produit ABIN8032301

Cet anticorps Lapin Polyclonal détecte spécifiquement RTKN2 dans FACS. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour RTKN2 anticorps (AA 1-572) (PE) (ABIN8032301)

Antigène: RTKN2 (Rhotekin 2 (RTKN2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RTKN2 est conjugé à/à la PE

Application: Flow Cytometry (FACS)

Détail du produit anti-RTKN2 anticorps (PE)

Épitope: AA 1-572

Fonction: Anti-RTKN2 Antibody PE Conjugated

Homologie: Human RTKN2 shares 71.8% amino acid (aa) sequence identity with mouse RTKN2.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human RTKN2 recombinant protein (Position: M1-D572). Human RTKN2 shares 71.8% amino acid (aa) sequence identity with mouse RTKN2.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry, Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: Each vial contains 50 % glycerol, 0.9 % NaCl, 0.2 % Na2HPO4, 0.02 % Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.

Date de péremption: 12 months

Détails sur RTKN2

Antigène: RTKN2 (Rhotekin 2 (RTKN2))

Autre désignation: RTKN2

Sujet:

Background: Rhotekin 2 is a protein in humans that is encoded by the RTKN2 gene. The RTKN2 gene encodes a protein known as Rhotekin-2, which is involved in various cellular processes, including cytoskeletal organization, cell migration, and signal transduction. RTKN2 interacts with Rho GTPases, particularly RhoA, and modulates their activity to regulate actin cytoskeleton dynamics and cell morphology. This protein plays a role in cell adhesion and migration, with implications for tissue development, wound healing, and cancer metastasis. Additionally, RTKN2 has been linked to synaptic plasticity and neuronal development in the brain. Dysregulation of RTKN2 expression or function has been associated with neurological disorders, cardiovascular diseases, and cancer progression. Elucidating the molecular mechanisms underlying RTKN2's diverse functions is crucial for understanding its physiological roles and its potential as a therapeutic target for various diseases.

Gene Full Name: rhotekin 2

ID gène: 219790

UniProt: Q8IZC4